Reye Syndrome. Reye syndrome, a disorder that causes sudden and dangerous liver and brain damage, is a side effect of aspirin therapy in children who have chickenpox or influenza. The disease can lead to coma and is life threatening. Symptoms include rash, vomiting, and confusion beginning about a week after the onset of the disease. Because of the strong warnings against children taking aspirin, this condition is, fortunately, very rare. Children should never be given aspirin when they have a viral infection or fever. Acetaminophen (Tylenol) is the preferred drug for fever or pain in patients younger than age 18 years.
Other Rare Complications of Chickenpox. Other extremely rare complications of varicella include problems in blood clotting and inflammation of the nerves in the hands and feet. Inflammation can also occur in other areas of the body, such as the heart, testicles, liver, joints, or kidney.
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